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Breakthrough Treatment for Eczema and Psoriasis


Clinical trial finds new treatment for psoriasis and atopic dermatitis

Eczema and psoriasis, two common skin conditions, can be quite challenging to manage. However, recent developments in skincare may offer new options for those affected. A clinical trial has studied a promising treatment called PF-07038124 that has shown significant potential in treating both eczema (atopic dermatitis) and psoriasis (plaque psoriasis). 

Clinical Trial

Researchers conducted the trial from December 2020 to August 2021 across multiple sites in four countries. They recruited 104 participants, aged 18 to 70, who had mild to moderate eczema or psoriasis covering a certain percentage of their body surface area. These participants were randomly assigned to receive either PF-07038124 topical ointment or a placebo (an inactive substance) daily for six weeks.


After six weeks of treatment, the results were compelling. Patients using PF-07038124 experienced significantly better outcomes compared to those using the placebo. For individuals with eczema, there was a remarkable 74.9% improvement in their Eczema Area and Severity Index (EASI) score, whereas the placebo group only saw a 35.5% improvement. Similarly, for those with psoriasis, PF-07038124 led to a notable decrease of 4.8 in their Psoriasis Area and Severity Index (PASI) score, while the placebo group showed minimal change.


The treatment was well-tolerated, with no reported adverse reactions at the application site.


These findings mark a significant advancement in the treatment of eczema and psoriasis. PF-07038124 offers a new option for individuals grappling with these conditions, providing a safe and effective alternative to alleviate symptoms and enhance quality of life. Unlike some treatments that may come with unwanted side effects or limited efficacy, PF-07038124 stands out as a well tolerated solution.


If you or someone you know is struggling with eczema or psoriasis, it is advisable to consult a healthcare provider about PF-07038124. This groundbreaking treatment could provide the relief you've been seeking, transforming the way we approach skincare and improving the lives of many individuals affected by these challenging conditions.


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JAMA Network, Dec-20-23

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This content is for informational and educational purposes only. It is not intended to provide medical advice or to take the place of such advice or treatment from a personal physician. All readers/viewers of this content are advised to consult their doctors or qualified health professionals regarding specific health questions. CenTrial Data Ltd. does not take responsibility for possible health consequences of any person or persons reading or following the information in this educational content. Treatments and clinical trials mentioned may not be appropriate or available for all trial participants. Outcomes from treatments and clinical trials may vary from person to person. Consult with your doctor as to whether a clinical trial is a suitable option for your condition. Assistance from generative AI tools may have been used in writing this article.