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Personalized Exercise and Diet Plans Could Help Treat NAFLD and Prediabetes


Clinical trial finds that diet and exercise has positive effect on gut bacteria

Nonalcoholic fatty liver disease (NAFLD) and prediabetes are two conditions that affect many people. One way to treat these conditions is through exercise and diet, but there isn't much known about how they affect the good bacteria in our gut.

NAFLD happens when too much fat builds up in the liver, and it can cause major health problems like liver damage and even liver failure. Prediabetes happens when the body has too much sugar in the blood, but not enough to be called diabetes. Both of these conditions are linked to the way we eat and how much we exercise.

Clinical Trial

A clinical trial looked at how exercise and diet can change the bacteria in our gut and how this might help people with NAFLD and prediabetes. The trial lasted for 8.6 months and included four groups of people: one group that did aerobic exercise, one group that changed their diet, one group that did both exercise and changed their diet, and a control group that did not do anything.

The researchers looked at three things in the trial: how much fat was in the liver, how well the body used sugar, and the bacteria in the gut. The results showed that the group that did both exercise and changed their diet had the best results for all three things. This group had more types of good bacteria in their gut and their bacteria were more stable.

It's important to know that there were no bad effects from exercise and diet changes. Also, the trial showed that not everyone responded to exercise and diet changes in the same way. The researchers used a special test to figure out who responded well and who didn't.

The researchers found that a personalized test of the bacteria in the gut could help predict how well a person would respond to exercise and diet changes. This means that doctors could do this test before they recommend an exercise and diet plan for their patient, to see if it will work for them.

Exercise and changing our diet are good ways to treat NAFLD and prediabetes because they can help us lose weight and make our bodies better at using insulin. Insulin is a hormone that helps our bodies use sugar.

The bacteria in our gut help us digest our food and do other important things. Sometimes, the balance of good and bad bacteria in our gut gets messed up and this can make us sick. When we exercise and change our diet, it can help balance out the good and bad bacteria in our gut.


This trial shows us that if we can figure out how to personalize our exercise and diet plans, we might be able to help people with NAFLD and prediabetes get better. By doing a special test to see what kind of bacteria is in their gut, we can predict how well they will respond to exercise and diet changes. This means that doctors can make better plans for their patients and help them get better faster.

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This content is for informational and educational purposes only. It is not intended to provide medical advice or to take the place of such advice or treatment from a personal physician. All readers/viewers of this content are advised to consult their doctors or qualified health professionals regarding specific health questions. CenTrial Data Ltd. does not take responsibility for possible health consequences of any person or persons reading or following the information in this educational content. Treatments and clinical trials mentioned may not be appropriate or available for all trial participants. Outcomes from treatments and clinical trials may vary from person to person. Consult with your doctor as to whether a clinical trial is a suitable option for your condition. Assistance from generative AI tools may have been used in writing this article.