New Hope for Abdominal Cancer Patients

Aug 11, 2020 by CenTrial



A new clinical trial is exploring a novel way to deliver chemotherapy to abdominal patients that requires only 10-20% of the normal dose and does not cause the patient to lose their hair.

When tumors spread to the peritoneum, a thin layer of tissue that lines the abdomen, they are very difficult to treat and are usually fatal.

This phase 1 trial is testing the efficacy of pressurized intraperitoneal aerosolized chemotherapy (PIPAC). In this new treatment, the abdomen is blown up like a balloon. Then liquid chemotherapy is sprayed into the space in a thin layer that coats all the crevices in the abdomen. After soaking for 30 minutes the medication is vacuumed out.

The trial is seeking patients with ovarian, uterine, gastric, and colorectal cancers who have not been helped by at least one previous chemotherapy treatment. Accepted participants will receive the PIPAC treatment every 6 weeks for a total of three cycles. The trial will last for three years and has treatment sites in Florida, New York, and Maryland.

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