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Clinical Trial shows Treating UTIs with Supplements instead of Antibiotics is Effective


Clinical trial confirms dietary supplement is safe and effective for treating UTIs instead of using antibiotics

Are you tired of dealing with the pain and discomfort of a urinary tract infection (UTI)? If so, you are not alone. UTIs are a common problem, particularly among women. Unfortunately, the overuse of antibiotics has led to an increase in antimicrobial resistance, making it challenging to treat these infections. Luckily, a clinical trial has found a potential alternative approach to treating and preventing UTIs.

Clinical Trial

The trial evaluated the effectiveness of a D-mannose-based dietary supplement called DAPAD complex for the treatment of uncomplicated acute E. coli UTIs. D-Mannose is a type of sugar found in certain fruits and vegetables. The DAPAD complex contains D-mannose, citric acid, prebiotic fibers, Astragalus, and dandelion.

The participants were non menopausal women who had an acute uncomplicated E. coli UTI. The UTI was diagnosed according to the presence of at least one urinary symptom and bacteriuria (bacteria in urine).

The DAPAD complex was administered twice a day for 5 days, with phenazopyridine and alkalizing agents as the standard of care. The control group received a placebo with standard of care. The subjective (clinical resolution/response) and objective (midstream bacteriuria) outcomes were evaluated at the end of therapy (day 6) and on day 35 of follow-up.

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The results of the study were very positive. People who took the DAPAD supplement had a higher chance of getting better at 6 days and 35 days compared to those who took the placebo. On day 35, none of the people who took the DAPAD supplement had symptoms, while some of the people who took the placebo did. The DAPAD supplement also helped more people eliminate the bacteria causing the infection on days 6 and 35. There were only three minor side effects, and they weren't related to the supplement. All of the side effects were treated by a doctor.


The DAPAD complex dietary supplement is an effective and safe treatment for acute uncomplicated E. coli UTIs. The supplement is particularly promising because it does not contribute to antimicrobial resistance, which is a significant concern when treating UTIs with antibiotics. This study provides hope for individuals suffering from UTIs and for healthcare professionals looking for alternative approaches to treating and preventing these infections.

If you suffer from UTIs, it is essential to consult with your healthcare provider before starting any new treatment. However, the results of this study suggest that the DAPAD complex dietary supplement may be a viable treatment option for some individuals. So, if you are tired of dealing with the discomfort of UTIs, talk to your healthcare provider about the potential benefits of the DAPAD complex.


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This content is for informational and educational purposes only. It is not intended to provide medical advice or to take the place of such advice or treatment from a personal physician. All readers/viewers of this content are advised to consult their doctors or qualified health professionals regarding specific health questions. CenTrial Data Ltd. does not take responsibility for possible health consequences of any person or persons reading or following the information in this educational content. Treatments and clinical trials mentioned may not be appropriate or available for all trial participants. Outcomes from treatments and clinical trials may vary from person to person. Consult with your doctor as to whether a clinical trial is a suitable option for your condition. Assistance from generative AI tools may have been used in writing this article.