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Can Penumbra System be used for Routine Treatment of Stroke Patients?


Clinical study finds Penumbra System valuable in treating stroke patients

With continued technological advancements, new techniques are being introduced for the treatment of various medical diseases. One such example is the Penumbra System designed for clot removal in patients with ischemic stroke.

Stroke is a leading cause of disability and death worldwide, and acute ischemic stroke, which occurs when a blood clot blocks a blood vessel in the brain, is the most common type of stroke. Treatment for acute ischemic stroke involves restoring blood flow to the affected area of the brain as quickly as possible, which can help prevent brain damage and improve outcomes.

Clinical Study

A clinical study has explored the safety and effectiveness of using the Penumbra System for the routine treatment of stroke patients.

One promising treatment for acute ischemic stroke is endovascular therapy, which involves using catheters and other specialized devices to remove the blood clot and restore blood flow to the affected area of the brain. The Penumbra System is one such device, and it has been shown to be effective in clinical trials. It is a thrombus removal system specifically designed to remove thrombus using aspiration. However, it is unclear how well the Penumbra System performs in routine clinical practice.

To address this question, a group of researchers conducted a clinical study using data from the COMPLETE Registry, which includes information on patients who underwent endovascular therapy for acute ischemic stroke using the Penumbra System at 42 different medical centers across the United States and Europe. The study involved 650 patients who underwent treatment with the penumbra system. The primary outcomes were the successful restoration of blood flow to the affected area as well as 90-day functional outcomes.

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The results of the clinical study showed that the Penumbra System was effective in restoring blood flow to the affected area of the brain in the majority of patients. Specifically, the researchers found that the Penumbra System achieved successful revascularization, or restoration of blood flow, in up to 87.8% of cases.

The study also looked at the clinical outcomes of patients who underwent endovascular therapy using the Penumbra System. The researchers found that patients who achieved successful revascularization had better functional outcomes than those who did not. The clinical trial demonstrated a mortality rate of only 15.5% in stroke patients undergoing the penumbra technique.


The results of the clinical study are promising and suggest that the Penumbra System is a safe and effective treatment option for acute ischemic stroke in routine clinical practice. This study provides valuable information on the effectiveness of the Penumbra System in routine clinical practice for the treatment of acute ischemic stroke. It suggests that the Penumbra System may be a safe therapeutic option for people with ischemic stroke. It is important to discuss all treatment options with your doctor before embarking on any treatment pathway for ischemic stroke.
Stroke Journal, Mar-22
ClinicalTrials.gov NCT03464565

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This content is for informational and educational purposes only. It is not intended to provide medical advice or to take the place of such advice or treatment from a personal physician. All readers/viewers of this content are advised to consult their doctors or qualified health professionals regarding specific health questions. CenTrial Data Ltd. does not take responsibility for possible health consequences of any person or persons reading or following the information in this educational content. Treatments and clinical trials mentioned may not be appropriate or available for all trial participants. Outcomes from treatments and clinical trials may vary from person to person. Consult with your doctor as to whether a clinical trial is a suitable option for your condition. Assistance from generative AI tools may have been used in writing this article.