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Enhancing Quality of Life in Muscle Disease Patients


Clinical trial shows ACT is beneficial for muscle disease patients

Imagine facing the challenges of muscle diseases that impact your daily life. From limited mobility to persistent pain, these conditions can significantly affect your overall quality of life. However, a clinical trial offers hope through a therapeutic approach called Acceptance and Commitment Therapy (ACT).

Muscle Diseases

Muscle diseases are conditions that affect the muscles, making them weaker or less functional. These conditions can lead to difficulties in moving, performing everyday tasks, and experiencing pain. As a result, the quality of life for individuals with muscle diseases can be compromised, affecting their emotional well-being, physical abilities, and social interactions. Currently, there are no curative treatments for muscle diseases so the emphasis is on the options that can help improve the quality of life in these patients.

Acceptance and Commitment Therapy

A group of researchers conducted a clinical trial to investigate whether a type of therapy called Acceptance and Commitment Therapy could help improve the quality of life for people living with muscle diseases. ACT is a form of psychological therapy that aims to enhance psychological flexibility – the ability to adapt and respond to challenging thoughts and emotions in a healthy way.

Clinical Trial

The researchers conducted a clinical trial involving a group of 155 individuals with muscle diseases and divided them into two groups. One group received the ACT intervention, while the other group did not. The researchers then observed and compared the changes in the participants' quality of life over 9 weeks. The quality of life was measured using the Individualised Neuromuscular Quality of Life Questionnaire (INQoL).

Results and Findings

The clinical trial’s results were promising. The participants who received Acceptance and Commitment Therapy showed significant improvements in their quality of life compared to those who did not undergo the therapy. The therapy helped participants manage their pain more effectively and cope with the challenges posed by their muscle diseases. Additionally, participants reported feeling better emotionally and having a more positive outlook on life.

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Why ACT Works

ACT focuses on accepting difficult thoughts and feelings rather than trying to avoid or eliminate them. This approach empowers individuals to let go of unhelpful strategies and engage in activities that matter to them, even in the face of challenges. For people with muscle diseases, this means learning to live a fulfilling life despite the limitations posed by their condition.

What This Means

The findings of this clinical trial offer hope for individuals living with muscle diseases. Acceptance and Commitment Therapy could potentially become an essential part of their treatment plans, helping them lead more satisfying and meaningful lives. By improving psychological flexibility and emotional well-being, ACT can provide tools to cope with pain and limitations, ultimately enhancing the overall quality of life.


Living with muscle diseases can be a challenging journey, impacting various aspects of daily life. The clinical trial introduces a ray of hope through Acceptance and Commitment Therapy. This therapeutic approach has shown promising results in enhancing the quality of life for people with muscle diseases. By fostering psychological flexibility and enabling individuals to embrace life despite challenges, ACT has the potential to make a meaningful difference in the lives of those facing these conditions. As research continues to evolve, this clinical trial marks a positive step toward a brighter future for individuals living with muscle diseases.
Psychological Medicine, Feb-23-22
ClinicalTrials.gov NCT02810028

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This content is for informational and educational purposes only. It is not intended to provide medical advice or to take the place of such advice or treatment from a personal physician. All readers/viewers of this content are advised to consult their doctors or qualified health professionals regarding specific health questions. CenTrial Data Ltd. does not take responsibility for possible health consequences of any person or persons reading or following the information in this educational content. Treatments and clinical trials mentioned may not be appropriate or available for all trial participants. Outcomes from treatments and clinical trials may vary from person to person. Consult with your doctor as to whether a clinical trial is a suitable option for your condition. Assistance from generative AI tools may have been used in writing this article.