A recent clinical trial has explored a new approach in the management of patients who have been discharged from the hospital following the life-saving treatment of sepsis.
Sepsis is a potentially life-threatening condition that occurs when the body's response to an infection damages its tissues and organs. The infection-fighting processes turn on the body, resulting in organ damage and dysfunction. Sepsis may progress to septic shock. This is a dramatic drop in blood pressure that can damage the lungs, kidneys, liver, and other organs. This can ultimately lead to death.
Early treatment of sepsis is done in the hospital with intravenous antibiotics, fluids, and other drugs. However, the management of these patients does not stop with discharge from the hospital as this disease can cause long-term health problems which need to be managed even after returning home.
Recently a clinical trial has shown promising results for a new approach to treating sepsis.
The clinical study, published in the Critical Care Medicine journal, has focused on a new program designed to help patients recover from sepsis more effectively. The program called the Multicomponent Sepsis Transition and Recovery Program (M-STRP), is a comprehensive approach to care that involves a range of interventions designed to improve outcomes for sepsis patients. The 30-day nurse-led recovery program includes telephone and electronic health record communication, post-discharge medication review, evaluation for new symptoms, monitoring of associated diseases, and a palliative care approach.
The clinical trial included 691 participants divided into two groups. One group received routine post-discharge care while the other group received additional Sepsis Transition and Recovery support (M-STRP).
The results of the clinical study showed that the rate of adverse events was lower in the M-STRP group compared to the usual care group (28.7% vs. 33.3%). The death rate was also lower in the special care group (9.5%) compared to the usual care group (12.0%). This demonstrates that M-STRP was effective in reducing both mortality and readmissions for sepsis patients during the first 30 days after discharge.
These results of the clinical trial are significant because sepsis is a major health concern, affecting millions of people around the world each year. While treatments for sepsis have improved over the years, there is still a need for more effective approaches to care. The M-STRP program offers a promising new option for improving outcomes for sepsis patients, and may ultimately help reduce the overall burden of this condition on the healthcare system.
In conclusion, the Multicomponent Sepsis Transition and Recovery Program (M-STRP) appears to be a promising new approach to care for sepsis patients. The results of this study show that the program is safe and effective in reducing both mortality and readmissions. As more research is conducted on this program, it may become a standard part of care for sepsis patients in the future.
Journal of Critical Care Medicine, Mar-22