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Transforming HIV Treatment Adherence with Mobile Health Solutions


Clinical trial finds that initially WiseApp helped HIV patients adhere to medical treatment, but the effect did not last

In the world of HIV treatment, sticking to medication is crucial for managing the disease. Not taking medications as prescribed can lead to the disease getting worse, being passed on to others, and even causing early deaths among people living with HIV. However, there's hope in the form of new phone-based tools, known as mHealth tools, which might help people take their medications better and make their treatments work better.

Clinical trial

A clinical trial was conducted in New York City to see how well a new mHealth tool called WiseApp could help people living with HIV stick to their treatment plans. The trial used a fair test, where some people used WiseApp, while others used a different program just for comparison. The participants in the trial were people who had difficulties following their prescribed HIV treatment.

WiseApp is not just a simple app; it's a whole package designed to help and encourage users to take their medicines regularly. It includes stories from people who've been through similar experiences, reminders that pop up on your phone, ways to track when you've taken your pills, questionnaires about health, chatrooms to talk to others, and a list of things to do every day to keep track. Both groups in the trial got a special pill bottle called CleverCap, but only the group using WiseApp could link the pill bottle to the app.


The trial found that at the beginning of the trial, the group using WiseApp did a lot better at taking their HIV medicines regularly compared to the other group. They showed a big improvement, going from taking around 48% of their pills to about 69% during the first two months of the trial. But as time went on, from the second month to the fourth, while the group using WiseApp still did better, the difference wasn't as big or as clear.

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When researchers looked more closely at the data, they didn't see much of a difference in the progress made by both groups after 3 or 6 months. This means that, although WiseApp helped a lot initially, its impact didn't stay strong over the entire trial period.

The trial's results show that WiseApp was good at getting people to take their HIV medicines properly when they started using it. However, as time went on, it didn't keep up the same level of improvement. Even though it started well, keeping people on track with their medications over a longer time seemed to be a bit challenging for WiseApp.

Despite this, the trial gives us useful insights into how phone-based tools like WiseApp can help people living with HIV to stick to their treatment plans. It tells us that while these tools can be helpful initially, they might need more work to keep their positive effects going for a long time.


WiseApp showed early success in helping people with HIV stick to their treatment plans. This trial teaches us that while these phone-based tools can start strong in supporting treatment, more research and improvements are needed to ensure they can help consistently over a longer period. This is important for improving the health of people living with HIV and managing their treatment effectively.


JAMIA, Dec-05-22

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This content is for informational and educational purposes only. It is not intended to provide medical advice or to take the place of such advice or treatment from a personal physician. All readers/viewers of this content are advised to consult their doctors or qualified health professionals regarding specific health questions. CenTrial Data Ltd. does not take responsibility for possible health consequences of any person or persons reading or following the information in this educational content. Treatments and clinical trials mentioned may not be appropriate or available for all trial participants. Outcomes from treatments and clinical trials may vary from person to person. Consult with your doctor as to whether a clinical trial is a suitable option for your condition. Assistance from generative AI tools may have been used in writing this article.