Are you struggling to lose weight despite following a traditional weight-loss program? A clinical trial suggests that the Regulation of Cues (ROC) weight loss program, which targets genetically determined appetitive traits, could be a viable alternative for adults looking to shed pounds.
The randomized clinical trial involved 271 adults with a body mass index (BMI) of 25 to 45 and no comorbidities that would interfere with participation. Participants were randomly assigned to one of four interventions: ROC, ROC plus behavioral weight loss (ROC+), behavioral weight loss (BWL), or an active comparator (AC). The participants were evaluated over 12 months of treatment and 12 months of follow-up.
The results showed that individuals in the ROC, ROC+, and BWL groups all experienced similar weight loss during treatment and follow-up. However, those with higher levels of food responsiveness lost more weight in the ROC and ROC+ groups than in the BWL or AC groups.
The ROC program is designed to regulate the cues that trigger overeating and weight gain. It specifically targets food responsiveness and satiety responsiveness, which are genetically determined appetitive traits that interact with the environment and can lead to overeating and weight gain. The ROC+ program combines ROC with traditional behavioral weight loss techniques, such as energy restriction, increasing physical activity, and behavior therapy techniques.