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Voriconazole Lavage provides New Treatment for Fungal Keratitis


Clinical trial finds voriconazole lavage is an effective treatment for fungal keratitis

Fungal keratitis is a serious eye infection caused by fungi. It can affect anyone, but it's more common in people who wear contact lenses or who have a weakened immune system. Fungal keratitis can cause a range of symptoms, including eye pain, redness, blurred vision, and sensitivity to light. If left untreated, it can lead to vision loss or even blindness. The infection can be caused by exposure to contaminated water, soil, or plant material, or by improper use or care of contact lenses. Treatment for fungal keratitis usually involves antifungal medications, which can be given as eye drops, pills, or injections. Prompt diagnosis and treatment are crucial to prevent further damage to the eye.

Clinical Trial

A clinical trial was conducted to test a new treatment for fungal keratitis. The trial involved 31 people who were randomly assigned to receive one of two treatments. One group received eye drops alone, while the other group received eye drops and a continuous lavage of a medicine called voriconazole. The researchers wanted to see which treatment was better at curing the infection after three months. They also measured other things like the size of the infection and the thickness of the cornea.

Trial Results

The results of the trial showed that both treatments were about the same at curing the infection after three months. However, the group that received the voriconazole lavage had better results in severe cases of infection. The researchers also found that the size of the infection was smaller in the group that received the lavage after just three days of treatment.

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This means that voriconazole lavage is a safe and effective way to help people with fungal keratitis. The treatment can be especially helpful for people who have severe cases of infection.

It's important to know the symptoms of fungal keratitis, such as redness, pain, and sensitivity to light. If you experience these symptoms, you should see a doctor right away to prevent further damage to your vision. Taking good care of your eyes and practicing good hygiene can help reduce your risk of getting this disease.


This clinical trial showed that voriconazole lavage is a safe and effective treatment for fungal keratitis. If you have any symptoms of this disease, be sure to see a doctor right away to get the help you need. By taking good care of your eyes and practicing good hygiene, you can reduce your risk of getting fungal keratitis in the first place.


Springer, Jan-16-23

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This content is for informational and educational purposes only. It is not intended to provide medical advice or to take the place of such advice or treatment from a personal physician. All readers/viewers of this content are advised to consult their doctors or qualified health professionals regarding specific health questions. CenTrial Data Ltd. does not take responsibility for possible health consequences of any person or persons reading or following the information in this educational content. Treatments and clinical trials mentioned may not be appropriate or available for all trial participants. Outcomes from treatments and clinical trials may vary from person to person. Consult with your doctor as to whether a clinical trial is a suitable option for your condition. Assistance from generative AI tools may have been used in writing this article.