Dental implants are a popular solution for missing teeth. But sometimes, there are challenges during the implantation process. One of these challenges is the pneumatization of the maxillary sinus. This can make it difficult or impossible to install the implants. So, researchers have been exploring regenerative techniques that can help to improve bone formation in the maxillary sinus.
A clinical trial looked at different materials that can be used to improve bone formation in the maxillary sinus. The trial involved 36 patients who had a sinus elevation procedure. The sinus was filled with one of three materials.
The first group received a combination of xenogenic bone and autogenous bone. Xenogenic bone comes from a different species like a cow or pig, while autogenous bone comes from the patient's own body. In this group, there was more autogenous bone than xenogenic bone. The second group received xenogenic bone and L-PRF (Leucocyte and platelet-rich fibrin), which is derived from the patient's own blood and contains growth factors that can help to promote healing. The third group received only xenogenic bone.
After eight months, bone biopsies were taken from the engrafted sites and analyzed. The results showed that the first group had significantly more newly formed bone tissue than the other two groups. The second group had the least amount of newly formed bone tissue. Additionally, the second group had fewer xenogenic bone particles and more connective tissue.
Based on these findings, the researchers concluded that a combination of autogenous and xenogenic bone is the best option for improving bone formation in the maxillary sinus, especially for patients who have large antral cavities.